Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056705 | 0.84 | PTGER1 (0.40) | L3MBTL1 | |
| SCHEMBL26132995 | 0.81 | MAPT (0.42) | HTR2CMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31056266 | 0.80 | HTR2C (0.46) | HTR2CHTR2AMAPTMAPK1TDP1 | |
| SCHEMBL31056681 | 0.78 | HTR2C (0.44) | HTR2CHTR2AMAPTMAPK1TDP1 | |
| SCHEMBL31056082 | 0.77 | KDM1A (0.45) | HTR2CHTR2ACCR5SLC6A4MAOB | |
| SCHEMBL589281 | 0.76 | HTR2C (0.50) | HTR2CHTR2AMAPTMAPK1TDP1 | |
| SCHEMBL8408319 | 0.74 | SLC6A4 (0.52) | HTR2CCCR5SLC6A4MAOBHTR2B | |
| SCHEMBL23700129 | 0.74 | HTR2C (0.48) | HTR2CHTR2AMAPTMAPK1TDP1 | |
| SCHEMBL31056166 | 0.74 | HTR2C (0.41) | HTR2CHTR2AMAPTL3MBTL1CCR5 | |
| SCHEMBL23700093 | 0.74 | HTR2C (0.47) | HTR2CHTR2ACCR5SLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |