Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056276 | 0.84 | HTR2C (0.40) | L3MBTL1 | |
| SCHEMBL31056825 | 0.81 | MCL1 (0.47) | PTGER1FOLH1MCL1DHODHEDNRA | |
| SCHEMBL26132995 | 0.79 | MAPT (0.42) | EDNRAL3MBTL1 | |
| SCHEMBL31056045 | 0.79 | PTGER1 (0.50) | PTGER1FOLH1MCL1KDM4EALDH1A1 | |
| SCHEMBL31056459 | 0.79 | FOLH1 (0.45) | PTGER1FOLH1MCL1KDM4EALDH1A1 | |
| SCHEMBL31056217 | 0.79 | FOLH1 (0.48) | PTGER1FOLH1MCL1KDM4EALDH1A1 | |
| SCHEMBL31056247 | 0.76 | FOLH1 (0.43) | PTGER1FOLH1MCL1KDM4EALDH1A1 | |
| SCHEMBL31056024 | 0.76 | LMNA (0.50) | ALDH1A1MRGPRX4 | |
| SCHEMBL6580918 | 0.75 | MAP4K4 (0.52) | PTGER1MRGPRX4XDH | |
| Lithium Ion SCHEMBL31056412 | 0.75 | RXRA (0.42) | PTGER1MCL1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |