Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056880 | 0.85 | KDM4E (0.51) | HSD17B10TPMTMAPTTSHRAPOBEC3A | |
| SCHEMBL17201011 | 0.80 | HSD17B10 (0.56) | HSD17B10TPMTLCKFYNAKR1C4 | |
| SCHEMBL17201182 | 0.80 | HSD17B10 (0.56) | HSD17B10TPMTLCKFYNAKR1C4 | |
| SCHEMBL2970067 | 0.77 | HSD17B10 (0.70) | HSD17B10TPMTLCKFYNMAPT | |
| SCHEMBL31336087 | 0.77 | HSD17B10 (0.56) | HSD17B10TPMTLCKFYNMAPT | |
| SCHEMBL28362779 | 0.76 | HSD17B10 (0.51) | HSD17B10TPMTLCKFYNAKR1C4 | |
| SCHEMBL16108030 | 0.76 | HSD17B10 (0.50) | HSD17B10TPMTLCKFYNAKR1C3 | |
| SCHEMBL15845984 | 0.75 | HSD17B10 (0.50) | HSD17B10TPMTLCKFYNGPR35 | |
| SCHEMBL27851655 | 0.75 | HSD17B10 (0.62) | HSD17B10TPMTLCKFYNMAPT | |
| SCHEMBL28799138 | 0.74 | HSD17B10 (0.61) | HSD17B10TPMTLCKFYNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |