Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380165 | 0.84 | HSD17B10 (0.61) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL6474002 | 0.83 | HSD17B10 (0.46) | HSD17B10GPR35TPMTALDH1A1HPGD | |
| SCHEMBL27820154 | 0.81 | HSD17B10 (0.61) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL762108 | 0.80 | KDM4E (0.50) | HSD17B10LCKFYNTSHRALDH1A1 | |
| SCHEMBL6772316 | 0.80 | HSD17B10 (0.44) | HSD17B10TPMTHTTALDH1A1HPGD | |
| SCHEMBL27887957 | 0.80 | ALDH1A1 (0.44) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL28362779 | 0.80 | HSD17B10 (0.51) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL6475603 | 0.78 | TSHR (0.49) | HSD17B10TPMTTSHRAPOBEC3GALDH1A1 | |
| SCHEMBL27711069 | 0.78 | HSD17B10 (0.55) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL20380155 | 0.78 | HSD17B10 (0.53) | HSD17B10LCKFYNGPR35TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |