Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056282 | 0.85 | HSD17B10 (0.56) | KDM4EPOLBHSD17B10TPMTTSHR | |
| SCHEMBL7405341 | 0.85 | GAA (0.46) | KDM4EPOLBHSD17B10GAATSHR | |
| SCHEMBL17201045 | 0.81 | HSD17B10 (0.42) | KDM4EPOLBHSD17B10GAATPMT | |
| SCHEMBL17201267 | 0.81 | SOS1 (0.48) | KDM4EPOLBHSD17B10GAATPMT | |
| SCHEMBL3709174 | 0.78 | HSD17B10 (0.49) | KDM4EPOLBHSD17B10GAATPMT | |
| SCHEMBL29023133 | 0.77 | KDM4E (0.51) | KDM4EPOLBHSD17B10GAATSHR | |
| SCHEMBL31056505 | 0.77 | SMN1; SMN2 (0.50) | KDM4EPOLBHSD17B10TPMTHTT | |
| SCHEMBL856900 | 0.77 | KDM4E (0.58) | KDM4EPOLBHSD17B10GAATSHR | |
| SCHEMBL3298748 | 0.76 | KDM4E (0.50) | KDM4EPOLBHSD17B10GAATSHR | |
| SCHEMBL21955060 | 0.75 | GAA (0.50) | KDM4EPOLBHSD17B10GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |