Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896072 | 0.85 | DRD2 (0.47) | DRD2DRD1DRD4HTR2ADRD3 | |
| SCHEMBL21488621 | 0.82 | GABRG2 (0.34) | DRD2DRD1DRD4HTR2ADRD3 | |
| SCHEMBL25887632 | 0.81 | MAPT (0.48) | DRD2DRD1DRD4HTR2ADRD3 | |
| SCHEMBL25308572 | 0.80 | MAPT (0.45) | DRD2DRD1DRD4HTR2ADRD3 | |
| SCHEMBL25306362 | 0.80 | MAPT (0.47) | DRD2DRD1DRD4HTR2ADRD3 | |
| SCHEMBL20636709 | 0.78 | KDM4E (0.50) | DRD2DRD1DRD4HTR2ADRD3 | |
| SCHEMBL4051803 | 0.78 | TP53 (0.65) | MAPTTP53KDM4EPOLBHSD17B10 | |
| SCHEMBL25308182 | 0.74 | MAPT (0.43) | DRD2DRD1DRD4HTR2ADRD3 | |
| SCHEMBL25023864 | 0.73 | KDM4E (0.72) | MAPTCYP1A2KDM4EPOLBKMT2A | |
| SCHEMBL31056020 | 0.73 | SMN1; SMN2 (0.44) | KDM4EKMT2AHSD17B10GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |