Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056635 | 0.91 | NR1H2 (0.48) | NR1H2NR1H3PDK1PDK2PDK3 | |
| SCHEMBL2726051 | 0.84 | PDK1 (0.53) | NR1H2NR1H3PDK1PDK2PDK3 | |
| SCHEMBL30053079 | 0.84 | PARP1 (0.51) | NR1H2NR1H3PDK1PDK2PDK3 | |
| SCHEMBL29324569 | 0.83 | TMEM97 (0.47) | PDK1PDK2PDK3PDK4TMEM97 | |
| SCHEMBL29369782 | 0.82 | PDK1 (0.52) | NR1H2NR1H3PDK1PDK2PDK3 | |
| SCHEMBL38661369 | 0.82 | PARP1 (0.50) | NR1H2NR1H3PDK1PDK2PDK3 | |
| SCHEMBL29324566 | 0.80 | NR1H2 (0.45) | NR1H2NR1H3ROCK2ABHD6PDE4B | |
| SCHEMBL31056551 | 0.79 | HTR2C (0.43) | PARP1TMEM97SIGMAR1NPC1RAB9A | |
| SCHEMBL31056723 | 0.79 | PARP1 (0.47) | NR1H2NR1H3PDK1PDK2PDK3 | |
| SCHEMBL31056529 | 0.79 | PARP1 (0.47) | NR1H2NR1H3PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |