Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056740 | 0.80 | NR1H2 (0.49) | NR1H2NR1H3ROCK2ABHD6MEN1 | |
| SCHEMBL29320343 | 0.78 | OPRD1 (0.39) | KDM4EMEN1KMT2A | |
| SCHEMBL20053162 | 0.75 | KDM4E (0.47) | USP30BTKKDM4EPKMRORC | |
| SCHEMBL27952715 | 0.75 | SMARCA2 (0.48) | USP30BTKKDM4EPKMSMARCA2 | |
| SCHEMBL29324570 | 0.75 | ALDH1A1 (0.39) | NR1H2NR1H3KDM4EMEN1KMT2A | |
| SCHEMBL30736753 | 0.75 | NAMPT (0.52) | KDM4EEEDRBBP4SUZ12EZH2 | |
| SCHEMBL31056950 | 0.75 | PDE4B (0.40) | NR1H2NR1H3USP30PKMEED | |
| SCHEMBL29320340 | 0.75 | PDE4B (0.40) | NR1H2NR1H3USP30PKMEED | |
| SCHEMBL28961486 | 0.74 | NR1H2 (0.48) | NR1H2NR1H3USP30MEN1KMT2A | |
| SCHEMBL21757345 | 0.73 | KDM4E (0.48) | USP30BTKKDM4EPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |