Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056854 | 0.86 | KDM4E (0.62) | KDM4EKMT2AMEN1EGLN1TP53 | |
| SCHEMBL15054071 | 0.86 | KDM4E (0.62) | KDM4EKMT2AMEN1EGLN1TP53 | |
| SCHEMBL28624165 | 0.79 | ALDH1A1 (0.58) | KDM4EKMT2AMEN1EGLN1ALDH1A1 | |
| SCHEMBL23360051 | 0.78 | KMT2A (0.53) | KDM4EKMT2AMEN1COMTEGLN1 | |
| SCHEMBL17113034 | 0.78 | KDM4E (0.71) | KDM4EKMT2AMEN1EGLN1TP53 | |
| SCHEMBL28615432 | 0.78 | EGLN1 (0.54) | KDM4EKMT2AMEN1EGLN1TP53 | |
| SCHEMBL17113200 | 0.75 | PSMD14 (0.56) | KDM4EKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL27872880 | 0.75 | KMT2A (0.46) | KDM4EKMT2AMEN1EGLN1TP53 | |
| SCHEMBL26984289 | 0.75 | ELANE (0.49) | KDM4EKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL31467097 | 0.75 | ELANE (0.49) | KDM4EKMT2AMEN1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214149-B | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-113214149-A | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2021-08-06 | — | — | CN | disclosed |