Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056880 | 0.85 | KDM4E (0.51) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL7404397 | 0.80 | GAA (0.42) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL21955060 | 0.79 | GAA (0.50) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL31743304 | 0.79 | GAA (0.50) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL7413037 | 0.79 | GAA (0.54) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL24820036 | 0.78 | SOS1 (0.48) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL5924266 | 0.78 | KDM4E (0.50) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL20328549 | 0.77 | KDM4E (0.42) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL17201278 | 0.76 | SOS1 (0.42) | GAAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL29562450 | 0.76 | KDM4E (0.49) | GAAKDM4EPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |