Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057607 | 0.87 | QPCT (0.42) | ALDH1A1QPCTMEN1KMT2AGAA | |
| SCHEMBL10787385 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1QPCTMEN1KMT2A | |
| SCHEMBL31057543 | 0.81 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1QPCTMEN1KMT2A | |
| SCHEMBL31491029 | 0.81 | QPCT (0.43) | ALDH1A1QPCTMEN1KMT2AGAA | |
| SCHEMBL31552005 | 0.81 | QPCT (0.43) | ALDH1A1QPCTMEN1KMT2AGAA | |
| SCHEMBL31057578 | 0.81 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1QPCTAPLNRBCHE | |
| SCHEMBL30710039 | 0.80 | QPCT (0.42) | ALDH1A1L3MBTL1QPCTMEN1KMT2A | |
| SCHEMBL10787375 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1QPCTMEN1KMT2A | |
| SCHEMBL26694781 | 0.80 | QPCT (0.42) | ALDH1A1L3MBTL1QPCTMEN1KMT2A | |
| SCHEMBL28158091 | 0.79 | ERN1 (0.56) | ALDH1A1MEN1KMT2AGAAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665735-A1 | KRAS INHIBITORS | Erasca, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2025245105-A1 | KRAS INHIBITORS | ERASCA, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| WO-2024173842-A1 | KRAS INHIBITORS | ERASCA, INC. (US) | 2024-08-22 | — | — | WO | disclosed |