SCHEMBL10787385

SCHEMBL10787385

COc1ccc(CN(Cc2ccc(OC)cc2)c2ccc(C)c(C=O)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
QPCT Q16769 3/20 0.45
TSPO P30536 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
SIRT5 Q9NXA8 1/20 0.43
APLNR P35414 2/20 0.41
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
SLC16A3 O15427 1/20 0.40
SLC16A1 P53985 1/20 0.40
BCL2A1 Q16548 2/20 0.40
BCHE P06276 1/20 0.39
ERN1 O75460 1/20 0.39
TRIM24 O15164 1/20 0.39
TYR P14679 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787375 0.89 ALDH1A1 (0.50) ALDH1A1L3MBTL1QPCTTSPOMEN1
SCHEMBL10788127 0.85 QPCT (0.49) ALDH1A1L3MBTL1QPCTLMNACNR1
SCHEMBL31057531 0.83 TSPO (0.40) ALDH1A1L3MBTL1QPCTTSPOMEN1
SCHEMBL31057481 0.83 ALDH1A1 (0.44) ALDH1A1L3MBTL1QPCTTSPOMEN1
SCHEMBL10787489 0.82 CYP2C19 (0.53) ALDH1A1QPCTLMNACNR2SLC16A3
SCHEMBL31057543 0.82 ALDH1A1 (0.39) ALDH1A1L3MBTL1QPCTTSPOMEN1
SCHEMBL6233097 0.77 APLNR (0.53) ALDH1A1QPCTLMNAAPLNRCNR1
SCHEMBL31057536 0.76 BCL2A1 (0.39) ALDH1A1L3MBTL1QPCTTSPOAPLNR
SCHEMBL31661058 0.76 QPCT (0.41) ALDH1A1L3MBTL1QPCTTSPOAPLNR
SCHEMBL31057578 0.76 ALDH1A1 (0.38) ALDH1A1L3MBTL1QPCTAPLNRBCL2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4642280-A PHTHALOCYANINES; SENSITIVE, STABLE, LOW RESIDUAL VOLTAGE MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1987-02-10 US disclosed