Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | NOS2 | P35228 | 3/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609744 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDMEN1KMT2AAPAF1 | |
| SCHEMBL20704159 | 0.80 | MEN1 (0.44) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL1844481 | 0.76 | HPGD (0.41) | SMN1; SMN2HPGDALDH1A1CCR1CCR5 | |
| SCHEMBL27756237 | 0.74 | CYP1A2 (0.42) | SMN1; SMN2MEN1KMT2AAPAF1RAB9A | |
| SCHEMBL14853027 | 0.73 | HPGD (0.67) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL3562229 | 0.72 | LRRK2 (0.46) | SMN1; SMN2HPGDMEN1KMT2AKDM4E | |
| SCHEMBL30296304 | 0.70 | TRPV4 (0.39) | SMN1; SMN2HPGDCCR1CCR5CCR8 | |
| SCHEMBL27031413 | 0.70 | TRPV4 (0.39) | SMN1; SMN2HPGDCCR1CCR5CCR8 | |
| SCHEMBL21609746 | 0.70 | POLB (0.33) | SMN1; SMN2MEN1KMT2AAPAF1RAB9A | |
| SCHEMBL20553520 | 0.70 | CYP1A2 (0.44) | SMN1; SMN2MEN1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469712-B | Substituted 2-heteroaryloxy pyridines and salts thereof, and their use as herbicides | 拜耳公司 | 2024-08-13 | — | — | CN | disclosed |