Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25555717 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL30587103 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL25556511 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL25556331 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL12217649 | 0.84 | HSD17B10 (0.63) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL29783185 | 0.84 | HSD17B10 (0.63) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL30587089 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL11775995 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL29895856 | 0.83 | HPGD (0.58) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL2255249 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525007-A | 1H-benzo [ B ] azepin-2 (3H) -one compounds, compositions and methods for treating cancer | 成都安泰康赛生物科技有限公司 | 2024-08-20 | — | — | CN | disclosed |