Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058565 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBHSD17B10MAPTCYP1A2 | |
| SCHEMBL25555717 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBHSD17B10MAPTCYP1A2 | |
| SCHEMBL25556511 | 0.78 | ALDH1A1 (0.51) | ALDH1A1POLBHSD17B10MAPTCYP1A2 | |
| SCHEMBL30587103 | 0.78 | ALDH1A1 (0.51) | ALDH1A1POLBHSD17B10MAPTCYP1A2 | |
| SCHEMBL21794443 | 0.77 | ALDH1A1 (0.50) | ALDH1A1POLBHSD17B10MAPTCYP1A2 | |
| SCHEMBL26317015 | 0.73 | CES2 (0.47) | ALDH1A1HSD17B10MAPTLMNAHTT | |
| SCHEMBL29783185 | 0.71 | HSD17B10 (0.63) | ALDH1A1POLBHSD17B10MAPTCYP1A2 | |
| SCHEMBL12217649 | 0.71 | HSD17B10 (0.63) | ALDH1A1POLBHSD17B10MAPTCYP1A2 | |
| SCHEMBL20339548 | 0.71 | KDM4E (0.51) | ALDH1A1POLBHSD17B10CYP2C19HPGD | |
| SCHEMBL29902945 | 0.71 | KDM4E (0.51) | ALDH1A1POLBHSD17B10CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088420-A1 | 1H-BENZO[B]AZEPIN-2(3H)-ONE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | Chengdu Anticancer Bioscience, Ltd. (CN) | 2023-05-25 | — | — | WO | disclosed |