Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113314 | 0.86 | GAA (0.43) | GAAMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL3117697 | 0.84 | RAB9A (0.35) | GAAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15312202 | 0.80 | GAA (0.43) | GAAMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL4668294 | 0.79 | GAA (0.42) | GAAMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL3105620 | 0.79 | GAA (0.42) | GAAMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL3117837 | 0.77 | LMNA (0.52) | GAAPOLB | |
| SCHEMBL3114202 | 0.76 | GAA (0.43) | GAAMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL5165086 | 0.74 | MAPT (0.53) | GAAMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL23367943 | 0.73 | MAPT (0.55) | GAAMAPTSMN1; SMN2KDM4EHTT | |
| SCHEMBL21652164 | 0.73 | MAPT (0.52) | GAAMAPTSMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575064-B2 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG (DE) | 2013-11-05 | — | — | US | disclosed |
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130274099-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274100-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274101-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| CN-102907432-A | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG | 2013-02-06 | — | — | CN | disclosed |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | GAA 132/4885MAPT 4293/4885SMN1; SMN2 3004/4885 |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | GAA 132/4885MAPT 4293/4885SMN1; SMN2 3004/4885 |
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | CAT, CYP1A2, GABBR1 | GAA 93/4885MAPT 4023/4885SMN1; SMN2 3381/4885 |
| US-20130274100-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | GAA 132/4885MAPT 4293/4885SMN1; SMN2 3004/4885 |
| US-20130274099-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | GAA 132/4885MAPT 4293/4885SMN1; SMN2 3004/4885 |
| US-20130274101-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | GAA 132/4885MAPT 4293/4885SMN1; SMN2 3004/4885 |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | GAA 132/4885MAPT 4293/4885SMN1; SMN2 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.