Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 5/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976817 | 1.00 | ECE1 (0.36) | ECE1MMEITGB2ICAM1ITGAL | |
| SCHEMBL7747031 | 0.86 | CA2 (0.44) | ECE1MMECA2MEN1KMT2A | |
| SCHEMBL2979490 | 0.86 | CA2 (0.41) | ECE1MMEITGB2ICAM1ITGAL | |
| SCHEMBL30542190 | 0.86 | CA2 (0.41) | ECE1MMEITGB2ICAM1ITGAL | |
| SCHEMBL30542191 | 0.86 | CA2 (0.41) | ECE1MMEITGB2ICAM1ITGAL | |
| SCHEMBL2979493 | 0.86 | CA2 (0.41) | ECE1MMEITGB2ICAM1ITGAL | |
| SCHEMBL3091760 | 0.82 | MME (0.36) | ECE1MMECA2MEN1KMT2A | |
| SCHEMBL3091754 | 0.82 | MME (0.36) | ECE1MMECA2MEN1KMT2A | |
| SCHEMBL2991077 | 0.81 | KMT2A (0.35) | ECE1MMECA2KMT2ACA1 | |
| SCHEMBL3086313 | 0.81 | KMT2A (0.35) | ECE1MMECA2KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |
| EP-0831066-A1 | Biodegradable Aspartic acid polymers for preventing scale formation in boilers | NALCO CHEMICAL COMPANY (US) | 1998-03-25 | — | — | EP | claimed |
| US-6184336-B1 | USEFUL AS CHELANTS IN WATER TREATMENT | NALCO CHEMICAL COMPANY | 2001-02-06 | — | — | US | disclosed |
| US-5929198-A | HIGH MOLECULAR WEIGHT POLYMERS MODIFIED WITH N-DERIVATIZED COMPOUNDS | NALCO CHEMICAL COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0832851-A1 | Biodegradable poly (amino acids), derivatized amino acid polymers and methods for making the same | Nalco Chemical Company (US) | 1998-04-01 | — | — | EP | disclosed |