Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GGH | Q92820 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | ECE1 | P42892 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991077 | 1.00 | KMT2A (0.35) | KMT2AALOX15BLMPMP22CA2 | |
| SCHEMBL2981389 | 0.87 | KMT2A (0.42) | KMT2AALOX15BLMPMP22CA2 | |
| SCHEMBL29531006 | 0.87 | KMT2A (0.42) | KMT2AALOX15BLMPMP22CA2 | |
| SCHEMBL2981394 | 0.87 | KMT2A (0.42) | KMT2AALOX15BLMPMP22CA2 | |
| SCHEMBL3098286 | 0.83 | MME (0.32) | KMT2AMMEECE1 | |
| SCHEMBL3098289 | 0.83 | MME (0.32) | KMT2AMMEECE1 | |
| SCHEMBL3098107 | 0.81 | FDPS (0.42) | CA2CA1 | |
| SCHEMBL3098199 | 0.81 | ENPEP (0.33) | MMEECE1 | |
| SCHEMBL3098192 | 0.81 | ENPEP (0.33) | MMEECE1 | |
| SCHEMBL3098115 | 0.81 | FDPS (0.42) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |