Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544807 | 0.81 | NAMPT (0.42) | KDM4EALDH1A1TSHRNAMPTKMT2A | |
| SCHEMBL31159075 | 0.80 | MTNR1A (0.51) | OPRD1KDM4ENAMPTPKMNOTUM | |
| SCHEMBL14559364 | 0.80 | MTNR1A (0.51) | OPRD1KDM4ENAMPTPKMNOTUM | |
| SCHEMBL31058860 | 0.79 | NAMPT (0.41) | OPRD1KDM4EALDH1A1NAMPTKMT2A | |
| SCHEMBL9543218 | 0.78 | CYP1A2 (0.44) | ALDH1A1NAMPTALOX5APNOTUM | |
| SCHEMBL3061256 | 0.78 | DRD2 (0.47) | ALDH1A1NAMPTMEN1KMT2AALOX5AP | |
| SCHEMBL29571640 | 0.78 | DRD2 (0.47) | ALDH1A1NAMPTMEN1KMT2AALOX5AP | |
| SCHEMBL30681381 | 0.78 | DRD2 (0.47) | ALDH1A1NAMPTMEN1KMT2AALOX5AP | |
| SCHEMBL1760601 | 0.78 | DRD2 (0.47) | ALDH1A1NAMPTMEN1KMT2AALOX5AP | |
| SCHEMBL30390423 | 0.78 | DRD2 (0.47) | ALDH1A1NAMPTMEN1KMT2AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525016-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2024-08-20 | — | — | CN | disclosed |