Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 4/20 | 0.48 |
| ▸ | BLM | P54132 | 4/20 | 0.48 |
| ▸ | CASP7 | P55210 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26151953 | 1.00 | SMARCA2 (0.51) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL26151952 | 0.75 | ADORA2A (0.44) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL31058892 | 0.75 | ADORA2A (0.44) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL10966608 | 0.75 | CDK5 (0.49) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL31064873 | 0.72 | ALDH1A1 (0.65) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL1165179 | 0.71 | GSK3B (0.47) | SMARCA2PBRM1ALDH1A1HSD17B10MAPT | |
| SCHEMBL29755699 | 0.69 | KDM4E (0.51) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL7116127 | 0.69 | KDM4E (0.51) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1253845 | 0.68 | MEN1 (0.47) | SMARCA2PBRM1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL8545080 | 0.68 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251389-A | Pyridyl derivatives as sodium channel activators | 泽农医药公司 | 2024-06-25 | — | — | CN | disclosed |