Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.45 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | PRKACA | P17612 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | LTK | P29376 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12100759 | 0.87 | MAP4K4 (0.46) | GSK3BNOS3NOS2PRKACAADORA2A | |
| SCHEMBL5973721 | 0.83 | MAPT (0.47) | NOS3NOS2ADORA2AAURKAMAP4K4 | |
| SCHEMBL15865503 | 0.81 | NOS3 (0.54) | GSK3BNOS3NOS2PRKACAADORA2A | |
| SCHEMBL4647645 | 0.81 | GSK3B (0.46) | GSK3BNOS3NOS2PRKACAADORA2A | |
| SCHEMBL29360194 | 0.81 | GSK3B (0.46) | GSK3BNOS3NOS2PRKACAADORA2A | |
| Iodide SCHEMBL31385461 | 0.81 | MAPT (0.46) | NOS3NOS2ADORA2AAURKAMAP4K4 | |
| SCHEMBL17565133 | 0.80 | CYP2A6 (0.50) | TDO2HSP90AA1PTK2ALDH1A1HSD17B10 | |
| SCHEMBL13730604 | 0.79 | NOS3 (0.52) | GSK3BNOS3NOS2AURKAMAP4K4 | |
| SCHEMBL11901650 | 0.79 | MAP4K4 (0.46) | NOS3NOS2TDO2AURKAMAP4K4 | |
| SCHEMBL17555671 | 0.79 | CDK2 (0.43) | GSK3BNOS3NOS2PRKACATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704184-A1 | ANTIOXIDANT POLYMERIC DIPHENYLAMINE COMPOSITIONS | BASF SE (DE) | 2020-09-09 | — | — | EP | claimed |
| CN-111278903-A | Antioxidant polymeric diphenylamine compositions | 巴斯夫欧洲公司 | 2020-06-12 | — | — | CN | claimed |
| US-20190127656-A1 | LUBRICANT COMPOSITIONS COMPRISING POLYMERIC DIPHENYLAMINE ANTIOXIDANTS | EXXONMOBIL RES & ENG CO (US) | 2019-05-02 | — | — | US | claimed |
| US-20190127526-A1 | Antioxidant Polymeric Diphenylamine Compositions | BASF INTERSERVICIOS S.A. DE C.V. (MX) | 2019-05-02 | — | — | US | claimed |
| US-11600791-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-03-07 | — | — | US | disclosed |
| EP-3936512-A1 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | Universal Display Corporation (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3424935-B1 | IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORP (US) | 2021-08-11 | — | — | EP | disclosed |
| US-20210050530-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
| US-10873038-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-12-22 | — | — | US | disclosed |
| EP-3704184-A1 | ANTIOXIDANT POLYMERIC DIPHENYLAMINE COMPOSITIONS | BASF SE (DE) | 2020-09-09 | — | — | EP | disclosed |
| CN-111333615-A | Heterocyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2020-06-26 | — | — | CN | disclosed |
| US-20200203630-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2020-06-25 | — | — | US | disclosed |
| US-20110034458-A1 | PYRIDINE METHYLENE AZOLIDINONES AND USE THEREOF PHOSPHOINOSITIDE INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2011-02-10 | — | — | US | disclosed |
| WO-2010003133-A2 | CDK MODULATORS | EXELIXIS INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
| CN-101052640-A | Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors | APPLIED RESEARCH SYSTEMS (AN) | 2007-10-10 | — | — | CN | disclosed |
| WO-2007020521-A1 | PYRIDOYRAZINONES AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-02-22 | — | — | WO | disclosed |
| EP-0099614-A2 | Nitro, amino and aroylamino-N-phenylpyridinamines and their use in a process for preparing pyrido(1,4)benzodiazapines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210050530-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | NUDC, NCL, NDC1 | GSK3B 3286/4885NOS3 777/4885NOS2 187/4885 |
| US-10873038-B2 | Organic electroluminescent materials and devices | NUDC, NCL, NDC1 | GSK3B 3286/4885NOS3 777/4885NOS2 187/4885 |
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | SLC6A4, SLC6A2, SLC6A3 | GSK3B 896/4885NOS3 678/4885NOS2 702/4885 |
| US-20110034458-A1 | PYRIDINE METHYLENE AZOLIDINONES AND USE THEREOF PHOSPHOINOSITIDE INHIBITORS | PIK3CD, PIK3CA, PTEN | GSK3B 752/4885NOS3 987/4885NOS2 1231/4885 |
| US-11600791-B2 | Organic electroluminescent materials and devices | NUDC, NCL, NDC1 | GSK3B 3286/4885NOS3 777/4885NOS2 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.