Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31059030 | 1.00 | LMNA (0.49) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31059017 | 0.81 | LMNA (0.55) | LMNATPMTALDH1A1POLBMAPT | |
| SCHEMBL31032711 | 0.78 | MAPK10 (0.41) | LMNAALDH1A1TSHRHTTMEN1 | |
| SCHEMBL290542 | 0.78 | LMNA (0.69) | LMNATPMTALDH1A1POLBMAPT | |
| SCHEMBL7368999 | 0.76 | LMNA (0.53) | LMNAPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL29142671 | 0.76 | LMNA (0.67) | LMNATPMTALDH1A1POLBMAPT | |
| SCHEMBL30874271 | 0.74 | ALOX15 (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL29243288 | 0.74 | ALOX15 (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL24253152 | 0.73 | LMNA (0.49) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL786462 | 0.72 | LMNA (0.60) | LMNATPMTALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388357-A | Heteroatom-containing chalcone derivative and preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-07-26 | — | — | CN | disclosed |