Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 8/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758598 | 1.00 | MAPK1 (0.36) | MAPK1RORCGPR119SYKCCNT1 | |
| SCHEMBL23317068 | 1.00 | MAPK1 (0.36) | MAPK1RORCGPR119SYKCCNT1 | |
| SCHEMBL23317063 | 0.86 | ACACB (0.34) | GPR119ACACB | |
| SCHEMBL31059155 | 0.86 | ACACB (0.34) | GPR119ACACB | |
| SCHEMBL31059139 | 0.86 | ACACB (0.35) | GPR119ACACB | |
| SCHEMBL23317472 | 0.86 | ACACB (0.35) | GPR119ACACB | |
| SCHEMBL23304675 | 0.86 | HCAR3 (0.36) | RORCCCNE1CDK2 | |
| SCHEMBL31059160 | 0.86 | GPR119 (0.33) | GPR119ACACBUSP30 | |
| SCHEMBL23317527 | 0.86 | GPR119 (0.33) | GPR119ACACBUSP30 | |
| SCHEMBL23317062 | 0.85 | ACACB (0.33) | GPR119ACACBUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929709-B | Spirocyclic O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside inhibitors | 比奥根MA公司 | 2024-08-30 | — | — | CN | disclosed |