Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25221940 | 1.00 | PRNP (0.38) | PRNPDPP4MAPTMEN1KMT2A | |
| SCHEMBL29257056 | 0.99 | PRNP (0.37) | PRNPDPP4MAPTMEN1KMT2A | |
| SCHEMBL30533423 | 0.85 | L3MBTL1 (0.43) | PRNPDPP4MAPTMEN1KMT2A | |
| SCHEMBL25224251 | 0.85 | L3MBTL1 (0.43) | PRNPDPP4MAPTMEN1KMT2A | |
| SCHEMBL30533422 | 0.85 | L3MBTL1 (0.43) | PRNPDPP4MAPTMEN1KMT2A | |
| SCHEMBL31253421 | 0.84 | MAPT (0.49) | PRNPMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25269253 | 0.84 | MAPT (0.40) | PRNPDPP4MAPTMEN1KMT2A | |
| SCHEMBL30533421 | 0.84 | MAPT (0.40) | PRNPDPP4MAPTMEN1KMT2A | |
| SCHEMBL26565362 | 0.79 | PTGS2 (0.34) | DPP4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31059246 | 0.78 | MEN1 (0.34) | MAPTMEN1KMT2ASMN1; SMN2CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504706-A | Macrocyclic compounds having farnesyl transferase inhibitory activity | 库拉肿瘤学公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-118339152-A | Macrocyclic compounds having farnesyl transferase inhibitory activity | 库拉肿瘤学公司 | 2024-07-12 | — | — | CN | disclosed |