Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25702840 | 0.92 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL30234432 | 0.92 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL3190767 | 0.90 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL1762653 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL16014641 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL1762446 | 0.88 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL951462 | 0.88 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL16014505 | 0.88 | NPC1 (0.40) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL29558577 | 0.88 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 | |
| SCHEMBL29860005 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PDE4BHSD11B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240308988-A1 | Method For Controlling Diamide Resistant Pests and Compounds Therefor | SYNGENTA CROP PROTECTION AG (CH) | 2024-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240308988-A1 | Method For Controlling Diamide Resistant Pests and Compounds Therefor | DDT, NOS1, SLC11A2 | ALDH1A1 784/4885SMN1; SMN2 2224/4885PDE4B 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.