Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.40 |
| ▸ | AKT1 | P31749 | 4/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.37 |
| ▸ | HTR3B | O95264 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038518 | 0.81 | LCK (0.41) | LCKGABRA5HTR3EHTR3BHTR3A | |
| SCHEMBL4036600 | 0.72 | LCK (0.73) | LCK | |
| SCHEMBL4041472 | 0.72 | LCK (0.70) | LCK | |
| SCHEMBL6645541 | 0.72 | PDE10A (0.49) | LCK | |
| SCHEMBL31026828 | 0.71 | CHEK1 (0.34) | LCK | |
| SCHEMBL1016624 | 0.70 | GABRA5 (0.36) | LCKGABRA5HTR3EHTR3BHTR3A | |
| SCHEMBL4036154 | 0.70 | LCK (0.71) | LCK | |
| SCHEMBL3320683 | 0.69 | HRH4 (0.36) | LCKGABRA5HTR3EHTR3BHTR3A | |
| SCHEMBL4042246 | 0.69 | LCK (0.35) | LCK | |
| SCHEMBL4036055 | 0.69 | LCK (0.58) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |