Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060236 | 0.84 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AALDH1A1DPP4 | |
| SCHEMBL23581559 | 0.83 | ADORA3 (0.57) | ADORA3ADORA1ADORA2AALDH1A1DPP4 | |
| SCHEMBL31061258 | 0.83 | ADORA3 (0.62) | ADORA3ADORA1ALDH1A1DPP4KDM4E | |
| SCHEMBL16474215 | 0.83 | ADORA3 (0.47) | ADORA3ADORA1ADORA2ABRD4RAB9A | |
| SCHEMBL16474223 | 0.83 | ADORA3 (0.47) | ADORA3ADORA1ADORA2ABRD4MAPT | |
| SCHEMBL31060180 | 0.79 | ADORA3 (0.63) | ADORA3ADORA1ADORA2AALDH1A1DPP4 | |
| SCHEMBL31060133 | 0.79 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AALDH1A1DPP4 | |
| SCHEMBL5848855 | 0.72 | KDM4E (0.44) | ADORA3ADORA1ADORA2AALDH1A1KDM4E | |
| SCHEMBL16147547 | 0.70 | KMT2A (0.46) | ADORA3ADORA1ADORA2AALDH1A1KDM4E | |
| SCHEMBL31060207 | 0.70 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |