Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14104420 | 0.84 | MEN1 (0.40) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL16146680 | 0.84 | ADORA3 (0.44) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL31060748 | 0.83 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL14441705 | 0.82 | RAB9A (0.45) | ADORA3ADORA2AMEN1KMT2AMAPT | |
| SCHEMBL16474215 | 0.81 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL14233654 | 0.77 | ADORA1 (0.49) | ADORA3ADORA1 | |
| SCHEMBL29366034 | 0.75 | CCR1 (0.42) | — | |
| SCHEMBL16474222 | 0.75 | TLR9 (0.50) | MAPTGAASMN1; SMN2 | |
| SCHEMBL11334542 | 0.74 | LMNA (0.33) | MEN1KMT2A | |
| SCHEMBL8902845 | 0.74 | CA1 (0.43) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353115-B2 | Immune system modulators | JANUS BIOTHERAPEUTICS, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140107115-A1 | NOVEL IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107115-A1 | NOVEL IMMUNE SYSTEM MODULATORS | HLA-DRB1, CD47, MYD88 | ADORA3 1152/4885ADORA1 581/4885ADORA2A 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.