Endiandrin A

Endiandrin A

SCHEMBL31060940

COc1cc([C@@H]2[C@@H](C)[C@H](C)[C@H]2c2ccc(O)c(OC)c2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 4/20 1.00
CA2 P00918 2/20 1.00
QDPR P09417 2/20 0.57
ALOX5 P09917 1/20 0.56
PTPN1 P18031 1/20 0.56
PPARG P37231 1/20 0.56
PPARD Q03181 1/20 0.56
MAOB P27338 1/20 0.53
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.53
KMT2A Q03164 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TSHR P16473 1/20 0.53
TRPA1 O75762 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14532805 0.83 NR3C1 (0.71) NR3C1CA2QDPRALOX5PTPN1
SCHEMBL11130424 0.81 QDPR (0.76) NR3C1CA2QDPRALOX5PTPN1
Nectandrin B SCHEMBL30678749 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG
Nectandrin B SCHEMBL12118675 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG
Nectandrin B SCHEMBL17145939 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG
Tetrahydrofuroguaiacin B SCHEMBL29484565 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG
Tetrahydrofuroguaiacin B SCHEMBL12118597 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG
Nectandrin B SCHEMBL893437 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG
Nectandrin B SCHEMBL893163 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG
Nectandrin B SCHEMBL29351645 0.80 NR3C1 (1.00) NR3C1CA2ALOX5PTPN1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
US-20250152601-A1 Compositions and Methods for the Treatment of Sexual Dysfunctions THE JONATHAN HURT LIVING TRUST (US) 2025-05-15 US disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed