SCHEMBL3106296

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13173678	0.89	PTGS2 (0.56)	AKR1C3KMT2AMEN1RAB9ARXFP1
	SCHEMBL13174673	0.89	AKR1C3 (0.55)	AKR1C3KMT2AMEN1RAB9ARXFP1
	SCHEMBL13174669	0.87	AKR1C3 (0.61)	AKR1C3KMT2AMEN1MAPTKDM4E
	SCHEMBL13174707	0.86	AKR1C3 (0.59)	AKR1C3KMT2AMEN1MAPTKDM4E
	SCHEMBL3104370	0.79	AKR1C3 (1.00)	AKR1C3KMT2AMEN1RAB9ANPC1
	SCHEMBL11981464	0.77	AKR1C3 (0.60)	AKR1C3KMT2AMEN1RXFP1MAPT
	SCHEMBL11981622	0.77	AKR1C3 (0.84)	AKR1C3KMT2AMEN1RAB9ANPC1
	SCHEMBL13175638	0.75	AKR1C3 (0.64)	AKR1C3
	SCHEMBL13173668	0.75	AKR1C3 (0.58)	AKR1C3KMT2AMEN1KDM4EHPGD
	SCHEMBL13174680	0.75	KMT2A (0.53)	AKR1C3KMT2AMEN1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.