Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451941 | 0.83 | ALDH1A1 (0.56) | NPC1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL24252451 | 0.83 | ALDH1A1 (0.56) | NPC1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL30819609 | 0.80 | HTR2C (0.53) | HTR2CHTR2BSLC6A4HTR6MAPT | |
| SCHEMBL4008574 | 0.80 | HTR2C (0.53) | HTR2CHTR2BSLC6A4HTR6MAPT | |
| SCHEMBL20384325 | 0.79 | HTR2C (0.38) | NPC1HTR2CHTR2BSLC6A4HTR6 | |
| SCHEMBL4013290 | 0.79 | HTR2C (0.52) | NPC1HTR2CHTR2BLMNAALDH1A1 | |
| SCHEMBL985592 | 0.79 | HTR2A (0.54) | NPC1HTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL29757994 | 0.79 | HTR2C (0.56) | HTR2CHTR2BLMNAALDH1A1MEN1 | |
| SCHEMBL23466495 | 0.79 | HTR2C (0.56) | HTR2CHTR2BLMNAALDH1A1MEN1 | |
| SCHEMBL3796606 | 0.79 | HTR2C (0.54) | NPC1HTR2CHTR2BLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |