Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.69 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677316 | 0.82 | FLT3 (0.54) | FLT3PDGFRBPDGFRAPOLBKDM4E | |
| SCHEMBL31060694 | 0.82 | FLT3 (1.00) | FLT3PDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL22074291 | 0.82 | KDM4E (0.60) | FLT3PDGFRBPDGFRAKDM4EHPGD | |
| SCHEMBL27874658 | 0.79 | RAB9A (0.61) | POLBNPC1RAB9AMAPTHPGD | |
| SCHEMBL5677321 | 0.78 | FLT3 (0.49) | FLT3PDGFRBPDGFRAPOLBNPC1 | |
| SCHEMBL31065648 | 0.78 | PDGFRB (0.50) | FLT3PDGFRBPDGFRAPOLBNPC1 | |
| SCHEMBL10514008 | 0.76 | POLB (0.49) | POLBNPC1RAB9AMAPTKDM4E | |
| SCHEMBL5675864 | 0.76 | MMP2 (0.51) | FLT3POLBNPC1RAB9AMAPT | |
| SCHEMBL27885276 | 0.75 | HRH4 (0.61) | FLT3PDGFRBPDGFRAPOLBMAPT | |
| SCHEMBL7079332 | 0.75 | FLT3 (0.54) | FLT3PDGFRBPDGFRAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637926-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | Universität Regensburg (DE) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024132278-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | UNIVERSITÄT REGENSBURG (DE) | 2024-06-27 | — | — | WO | disclosed |