Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25541553 | 0.84 | HTR2A (0.70) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL31742680 | 0.84 | HTR2A (0.70) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL25459268 | 0.84 | HTR2A (0.55) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL25459270 | 0.83 | HTR2A (0.54) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL20970923 | 0.82 | HTR2A (0.58) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL29633100 | 0.82 | HTR2A (0.58) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL20898335 | 0.82 | HTR2A (0.61) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL30681648 | 0.80 | HTR2A (0.51) | HTR2AHTR2CHTR2BHTR1AMTNR1A | |
| SCHEMBL26479058 | 0.80 | POLB (0.47) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL25459274 | 0.79 | HTR2A (0.59) | HTR2AHTR2CHTR2BHTR1AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287107-A1 | PRODRUGS OF DIMETHYLTRYPTAMINE AND DERIVATIVES THEREOF | ATAI THERAPEUTICS INC (US) | 2024-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287107-A1 | PRODRUGS OF DIMETHYLTRYPTAMINE AND DERIVATIVES THEREOF | HTR2B, TPH1, MAOB | HTR2A 13/4885HTR2C 27/4885HTR2B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.