SCHEMBL29633100

SCHEMBL29633100

C[N+](C)(C)CCc1c[nH]c2cccc(OP(=O)([O-])O)c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 9/20 0.58
▸ HTR2C P28335 4/20 0.58
▸ HTR1A P08908 3/20 0.58
▸ HTR2B P41595 3/20 0.58
▸ MTNR1A P48039 1/20 0.45
▸ MTNR1B P49286 1/20 0.45
▸ HTR6 P50406 2/20 0.43
▸ SCN5A Q14524 1/20 0.38
▸ SCN2A Q99250 1/20 0.38
▸ CHRM2 P08172 1/20 0.38
▸ CHRM1 P11229 1/20 0.38
▸ CHRM3 P20309 1/20 0.38
▸ DRD1 P21728 1/20 0.37
▸ HTR1D P28221 1/20 0.37
▸ HTR1B P28222 1/20 0.37
▸ HTR1E P28566 1/20 0.37
▸ ADORA2A P29274 1/20 0.37
▸ ADORA2B P29275 1/20 0.37
▸ HTR7 P34969 1/20 0.37
▸ DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20970923 1.00 HTR2A (0.58) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL25541553 0.90 HTR2A (0.70) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL31742680 0.90 HTR2A (0.70) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL25459268 0.90 HTR2A (0.55) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL25459274 0.89 HTR2A (0.59) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL25459270 0.89 HTR2A (0.54) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL25459146 0.88 HTR2A (0.58) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL30681648 0.86 HTR2A (0.51) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL31066854 0.82 HTR2A (0.60) HTR2AHTR2CHTR1AHTR2BMTNR1A
SCHEMBL23057152 0.79 MTNR1A (0.53) HTR2AHTR2CHTR1AHTR2BMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12611417-B1 Compositions and methods to inhibit acid-catalyzed dephosphorylation of phosphoryloxytryptamines Convergent Health Sciences LLC: (US) 2026-04-28 — — US disclosed
US-12503713-B1 Stabilization of tryptamines by denaturing enzymes, optimizing ionization states, and controlling confounding variables Convergent Health Sciences LLC (US) 2025-12-23 — — US disclosed
US-12497637-B1 Stabilization of tryptamines by denaturing enzymes, optimizing ionization states, and controlling confounding variables Convergent Health Sciences LLC (US) 2025-12-16 — — US disclosed
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 — — EP disclosed
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 — — US disclosed
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 — — US disclosed
EP-4452986-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-10-30 — — EP disclosed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 — — WO disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 — — US disclosed
WO-2023225043-A1 TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-11-23 — — WO disclosed
EP-4251181-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS Wesana Health Inc. (US) 2023-10-04 — — EP disclosed
EP-4251139-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE Wesana Health Inc. (US) 2023-10-04 — — EP disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 — — WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 — — WO disclosed
US-20220331344-A1 ORAL FORMULATIONS OF PSYCHOTROPIC MACROFUNGUS BOTANICAL EXTRACTS WITH MOUTHFEEL EXPERIENCE ENHANCERS CHICAGO ATLANTIC ADMIN, LLC 2022-10-20 — — US disclosed
WO-2022115798-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE WESANA HEALTH INC. (US) 2022-06-02 — — WO disclosed
WO-2022115796-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS WESANA HEALTH INC. (US) 2022-06-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611417-B1 Compositions and methods to inhibit acid-catalyzed dephosphorylation of phosphoryloxytryptamines PLCB1, PHKG1, PLCB3 HTR2A 105/4885HTR2C 39/4885HTR1A 91/4885
US-20220331344-A1 ORAL FORMULATIONS OF PSYCHOTROPIC MACROFUNGUS BOTANICAL EXTRACTS WITH MOUTHFEEL EXPERIENCE ENHANCERS MB, MLEC, NISCH HTR2A 53/4885HTR2C 26/4885HTR1A 76/4885
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR2A 5/4885HTR2C 4/4885HTR1A 8/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR2A 377/4885HTR2C 1196/4885HTR1A 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback