Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18605130 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL18865550 | 0.84 | SLC34A1 (0.44) | ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL18622981 | 0.81 | KDM4E (0.53) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL3281219 | 0.79 | MAPK1 (0.56) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL17064934 | 0.78 | KMT2A (0.45) | ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL3829511 | 0.78 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL31067457 | 0.78 | KMT2A (0.45) | ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL31067528 | 0.78 | SCN9A (0.44) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL3831590 | 0.78 | SCN9A (0.44) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL12832342 | 0.77 | POLB (0.42) | ALDH1A1KDM4EMAPTCTSKNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |