Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064740 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP17A1ALDH1A1HIF1ALMNA | |
| SCHEMBL31067705 | 0.84 | MAPT (0.50) | SMN1; SMN2CYP17A1LMNAL3MBTL1GRM8 | |
| SCHEMBL17064638 | 0.84 | MAPT (0.50) | SMN1; SMN2CYP17A1LMNAL3MBTL1GRM8 | |
| SCHEMBL9527174 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HIF1ALMNAGRM8 | |
| SCHEMBL31067515 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HIF1ALMNAGRM8 | |
| SCHEMBL9593024 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP17A1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7116027 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP17A1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL31067521 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HIF1ALMNAL3MBTL1 | |
| SCHEMBL17064620 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HIF1ALMNAL3MBTL1 | |
| SCHEMBL17064655 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP17A1LMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |