Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527174 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL31067609 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL17064740 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL9198122 | 0.81 | LMNA (0.51) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL31067431 | 0.81 | VCAM1 (0.54) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL9523568 | 0.81 | VCAM1 (0.54) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL17064620 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL31067521 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL2340870 | 0.79 | EPAS1 (0.56) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL27519799 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |