Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064638 | 1.00 | MAPT (0.50) | MAPTLMNAHSP90AA1SMN1; SMN2MEN1 | |
| SCHEMBL31067609 | 0.84 | SMN1; SMN2 (0.49) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17064740 | 0.84 | SMN1; SMN2 (0.49) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31067431 | 0.83 | VCAM1 (0.54) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9523568 | 0.83 | VCAM1 (0.54) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL15647693 | 0.80 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2CYP17A1CYP3A4CYP2D6 | |
| SCHEMBL9593024 | 0.78 | SMN1; SMN2 (0.54) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7116027 | 0.77 | SMN1; SMN2 (0.62) | MAPTLMNASMN1; SMN2KMT2ACYP17A1 | |
| SCHEMBL10222538 | 0.77 | SMN1; SMN2 (0.43) | MAPTLMNAHSP90AA1SMN1; SMN2MEN1 | |
| SCHEMBL11711222 | 0.76 | SMN1; SMN2 (0.50) | MAPTLMNAHSP90AA1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |