Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.82 |
| ▸ | EGFR | P00533 | 6/20 | 0.75 |
| ▸ | KIT | P10721 | 1/20 | 0.72 |
| ▸ | AURKA | O14965 | 1/20 | 0.68 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.68 |
| ▸ | BRAF | P15056 | 1/20 | 0.67 |
| ▸ | GAK | O14976 | 1/20 | 0.67 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.67 |
| ▸ | STK10 | O94804 | 1/20 | 0.67 |
| ▸ | RET | P07949 | 1/20 | 0.67 |
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.67 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.67 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.67 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.67 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.67 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.67 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473780 | 0.91 | EGFR (0.78) | KDREGFRGAKRIPK2STK10 | |
| SCHEMBL31067615 | 0.91 | KDR (0.80) | KDREGFRKITAURKAAURKB | |
| SCHEMBL31067650 | 0.90 | KDR (0.83) | KDREGFRKITAURKAAURKB | |
| SCHEMBL31067640 | 0.90 | KDR (0.84) | KDREGFRKITAURKAAURKB | |
| SCHEMBL31067666 | 0.90 | KDR (1.00) | KDREGFRKITAURKAAURKB | |
| Hydrochloric Acid SCHEMBL1507577 | 0.89 | EGFR (0.78) | KDREGFRGAKRIPK2STK10 | |
| SCHEMBL31067662 | 0.89 | EGFR (0.82) | KDREGFRKITAURKAAURKB | |
| SCHEMBL31067633 | 0.89 | KDR (0.82) | KDREGFRKITAURKAAURKB | |
| SCHEMBL31067741 | 0.87 | KDR (0.79) | KDREGFRKITAURKAAURKB | |
| SCHEMBL31067608 | 0.86 | KDR (0.85) | KDREGFRKITAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530175-A | PDGFR inhibitor and preparation method and application thereof | 中国药科大学 | 2024-08-23 | — | — | CN | disclosed |