SCHEMBL31068047

SCHEMBL31068047

O=c1oc(-c2cc(C(F)F)nn2-c2ncccc2Cl)nc2c(Cl)c3ccccc3cc12

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LIMK1 P53667 2/20 0.32
▸ LIMK2 P53671 2/20 0.32
▸ F2 P00734 1/20 0.32
▸ F10 P00742 1/20 0.32
▸ F7 P08709 1/20 0.32
▸ F3 P13726 1/20 0.32
▸ C1R P00736 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25083076 1.00 LIMK1 (0.32) LIMK1LIMK2F2F10F7
SCHEMBL25083078 0.87 F2 (0.31) F2F10F7F3C1R
SCHEMBL31068045 0.87 F2 (0.31) F2F10F7F3C1R
SCHEMBL15972092 0.86 LIMK1 (0.33) LIMK1LIMK2C1RALDH1A1
SCHEMBL950314 0.86 DHODH (0.40) F2F10F7F3C1R
SCHEMBL12528253 0.86 CYP1A2 (0.35) F2F10F7F3C1R
SCHEMBL951016 0.86 PDPK1 (0.36) F2F10F7F3C1R
SCHEMBL15971589 0.84 RAB9A (0.35) LIMK1LIMK2
SCHEMBL15971433 0.84 LIMK1 (0.34) LIMK1LIMK2F2F10F7
SCHEMBL25083045 0.84 DHODH (0.36) F2F10F7F3C1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-08-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR DDT, NOS1, SLC11A2 LIMK1 2549/4885LIMK2 3248/4885F2 1711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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