SCHEMBL31069245

SCHEMBL31069245

CS(=O)(=O)CCCn1c(Cn2c(=O)n(C3CC3)c3ccc(F)cc32)cc2cc(CN)ccc21

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
CACNA1G O43497 2/20 0.37
CACNA1H O95180 2/20 0.37
CTSS P25774 1/20 0.35
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31069343 0.93 CYP3A4 (0.34) CYP3A4CACNA1GCACNA1HCTSS
SCHEMBL31069311 0.90 CACNA1G (0.31) CACNA1GCACNA1HALDH1A1POLBNPSR1
SCHEMBL31069322 0.89 CACNA1G (0.40) CYP3A4CACNA1GCACNA1HALDH1A1POLB
SCHEMBL9974839 0.88 CACNA1G (0.36) CYP3A4CACNA1GCACNA1HCTSSALDH1A1
SCHEMBL9974858 0.88 CTSS (0.44) CTSS
SCHEMBL31069392 0.88 PARG (0.36)
SCHEMBL31069408 0.88 CYP3A4 (0.38) CYP3A4CACNA1GCACNA1HALDH1A1POLB
SCHEMBL31069310 0.87 CYP3A4 (0.44) CYP3A4
SCHEMBL31069404 0.86 CYP3A4 (0.48) CYP3A4CACNA1GCACNA1HNPSR1
SCHEMBL31069305 0.85 CYP3A4 (0.41) CYP3A4CACNA1GCACNA1HALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024174953-A1 BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF 苏州隆博泰药业有限公司 2024-08-29 WO claimed
WO-2024174953-A1 BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF 苏州隆博泰药业有限公司 2024-08-29 WO disclosed