Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DNM1L | O00429 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645566 | 1.00 | TGFBR1 (0.40) | TGFBR1LMNAPOLBTP53MAPT | |
| SCHEMBL23645565 | 1.00 | TGFBR1 (0.40) | TGFBR1LMNAPOLBTP53MAPT | |
| SCHEMBL23645382 | 0.86 | MAPT (0.42) | LMNAPOLBTP53MAPTTRPV1 | |
| SCHEMBL31069238 | 0.86 | MAPT (0.42) | LMNAPOLBTP53MAPTTRPV1 | |
| SCHEMBL23645385 | 0.86 | MAPT (0.42) | LMNAPOLBTP53MAPTTRPV1 | |
| SCHEMBL23645366 | 0.71 | TGFBR1 (0.49) | TGFBR1LMNATP53NPC1RAB9A | |
| SCHEMBL31069264 | 0.71 | TGFBR1 (0.49) | TGFBR1LMNATP53NPC1RAB9A | |
| SCHEMBL29724054 | 0.67 | TGFBR1 (0.53) | TGFBR1LMNATP53NPC1RAB9A | |
| SCHEMBL29724051 | 0.67 | TGFBR1 (0.52) | TGFBR1LMNATP53NPC1RAB9A | |
| SCHEMBL29724057 | 0.66 | TGFBR1 (0.55) | TGFBR1LMNATP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-B | Novel heteroatom aromatic amide derivative and pharmaceutical agent containing same | 科研制药株式会社 | 2024-08-20 | — | — | CN | disclosed |