SCHEMBL31069474

SCHEMBL31069474

c1ccc2c3c(ccc2c1)-c1ccc2cnccc2c1C3

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.45
CYP3A4 P08684 3/20 0.44
KDM4E B2RXH2 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
LMNA P02545 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAPKAPK2 P49137 1/20 0.44
CDK4 P11802 1/20 0.44
CCND1 P24385 1/20 0.44
TNF P01375 1/20 0.41
IKBKE Q14164 1/20 0.40
TBK1 Q9UHD2 1/20 0.40
CYP11B1 P15538 5/20 0.39
CYP11B2 P19099 4/20 0.39
CYP17A1 P05093 2/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30239992 0.83 CDK1 (0.39) HTTCYP3A4KDM4ECYP1A2CYP2C19
SCHEMBL27963572 0.83 CDK1 (0.39) HTTCYP3A4KDM4ECYP1A2CYP2C19
SCHEMBL30239986 0.83 CDK1 (0.39) HTTCYP3A4KDM4ECYP1A2CYP2C19
SCHEMBL31666454 0.83 TNF (0.39) HTTKDM4ECYP1A2CYP2C19LMNA
SCHEMBL868515 0.83 ALDH1A1 (0.52) HTTKDM4ECYP1A2CYP2C19CYP2C9
SCHEMBL29398977 0.81 CYP3A4 (0.57) HTTCYP3A4KDM4ECYP1A2CYP2C19
SCHEMBL3693486 0.81 CYP3A4 (0.57) HTTCYP3A4KDM4ECYP1A2CYP2C19
SCHEMBL17184068 0.79 CYP3A4 (0.55) HTTCYP3A4KDM4ECYP1A2CYP2C19
SCHEMBL30719863 0.77 HPRT1 (0.61) HTTCYP3A4KDM4ECYP1A2CYP2C19
SCHEMBL29539263 0.77 HPRT1 (0.61) HTTCYP3A4KDM4ECYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265343-A Organic light emitting diode and organic light emitting device 乐金显示有限公司 2024-06-28 CN disclosed