SCHEMBL868515

SCHEMBL868515

c1ccc2c3c(ccc2c1)-c1ccc2ccccc2c1C3

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 3/20 0.52
CYP2A6 P11509 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
HPRT1 P00492 1/20 0.48
CYP1A2 P05177 3/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 2/20 0.44
CYP2C19 P33261 2/20 0.44
HTT P42858 1/20 0.44
CDK5 Q00535 1/20 0.44
CDK5R1 Q15078 1/20 0.44
NCOA1 Q15788 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
DNMT1 P26358 1/20 0.42
ANPEP P15144 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28857916 0.91 HPRT1 (0.58) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Benzo(A)Fluorene SCHEMBL150250 0.85 CA1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Benzo(A)Fluorene SCHEMBL29413802 0.85 CA1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Benzo(A)Fluorene SCHEMBL29432662 0.85 CA1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Benzo(A)Fluorene SCHEMBL29620372 0.85 CA1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL5026739 0.84 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL4855174 0.83 ALDH1A1 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL31069474 0.83 HTT (0.45) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL30585507 0.82 ANPEP (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1155357 0.82 ANPEP (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120074336-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) 2012-03-29 US claimed
US-7964722-B2 Light-driven rotary molecular motors BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-06-21 US claimed
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS NATIONAL SCIENCE FOUNDATION 2011-03-31 US claimed
CN-117203190-A Compound for organic optoelectronic element, composition for organic optoelectronic element comprising same, organic optoelectronic element, and display device 三星SDI株式会社 2023-12-08 CN disclosed
US-11555028-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2023-01-17 US disclosed
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2019-04-25 US disclosed
EP-2291342-B1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KK (JP) 2014-06-04 EP disclosed
US-8431249-B2 Dibenzo[C,G]fluorene compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2013-04-30 US disclosed
US-8377574-B2 Dibenzo[c,g]fluorene compound and an organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2013-02-19 US disclosed
US-20120074336-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) 2012-03-29 US disclosed
US-20110260150-A1 DIBENZO[C,G]FLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2011-10-27 US disclosed
US-7964722-B2 Light-driven rotary molecular motors BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-06-21 US disclosed
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS NATIONAL SCIENCE FOUNDATION 2011-03-31 US disclosed
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-02-24 US disclosed
US-7838130-B2 Aminodibenzofluorene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-23 US disclosed
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-10-29 US disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME L1CAM, DDC, LEF1 ALDH1A1 35/4885HSD17B10 3694/4885CYP2A6 2100/4885
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS CCNA2, CCNO, SCO2 ALDH1A1 4255/4885HSD17B10 2681/4885CYP2A6 3535/4885
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT SCN2B, MRPS22, CTNNA1 ALDH1A1 908/4885HSD17B10 1632/4885CYP2A6 579/4885
US-11555028-B2 Organic compound and photoelectric conversion element SCN2B, MRPS22, CTNNA1 ALDH1A1 908/4885HSD17B10 1632/4885CYP2A6 579/4885
US-20110260150-A1 DIBENZO[C,G]FLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME GNG2, RARG, FRG1 ALDH1A1 2076/4885HSD17B10 3609/4885CYP2A6 2278/4885
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME LEF1, GNG2, SCO2 ALDH1A1 271/4885HSD17B10 1724/4885CYP2A6 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.