SCHEMBL31069484

SCHEMBL31069484

NC(=O)c1cn(-c2ccc(F)cc2)ccc1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
COMT P21964 1/20 0.41
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41
TUBB1 Q9H4B7 1/20 0.41
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31211696 0.85 KMT2A (0.50) KMT2ACOMTTUBB4ATUBBTUBA3C
SCHEMBL20176828 0.83 COMT (0.41) KMT2ACOMTCA12CA1CA2
SCHEMBL27933775 0.79 TUBB4A (0.52) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL4645055 0.70 TUBB4A (0.54) KMT2ATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL715572 0.69 CA12 (0.47) CA12CA1CA2CA9KDM4E
SCHEMBL1161158 0.69 TYK2 (0.50) KMT2AKDM4ELMNAALDH1A1MEN1
SCHEMBL16422627 0.69 MAPT (0.45) KMT2ATUBB4ATUBBTUBA3CTUBA1B
Hydrochloric Acid SCHEMBL23071632 0.68 TYK2 (0.49) KMT2AKDM4ELMNAALDH1A1MEN1
SCHEMBL31512160 0.68 LMNA (0.41) KMT2ACA12CA1CA2CA9
SCHEMBL29814385 0.67 LMNA (0.47) KMT2ACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240252688-A1 COMPOSITIONS AND METHODS FOR ENHANCED PROTEIN PRODUCTION HDT BIO CORP. 2024-08-01 US disclosed