Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 12/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22470576 | 0.85 | SCN1A (0.38) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL29714020 | 0.85 | SCN1A (0.38) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL25380407 | 0.83 | SCN1A (0.49) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL31069723 | 0.83 | ALKBH1 (0.37) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL31069731 | 0.83 | SCN1A (0.49) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL25438155 | 0.82 | GRM2 (0.37) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL31069727 | 0.82 | GRM2 (0.37) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL25380390 | 0.78 | TNIK (0.41) | CACNA2D1SLC6A2SCN1ASCN4AKCNH2 | |
| SCHEMBL31069722 | 0.78 | TNIK (0.41) | CACNA2D1SLC6A2SCN1ASCN4AKCNH2 | |
| SCHEMBL31118862 | 0.75 | SCN1A (0.55) | SCN1ASCN4AKCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118556044-A | Fused heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-08-27 | — | — | CN | disclosed |