Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25438155 | 1.00 | GRM2 (0.37) | GRM2SCN10ASCN1ASCN4AKCNH2 | |
| SCHEMBL29714020 | 0.84 | SCN1A (0.38) | GRM2SCN10ASCN1ASCN4AKCNH2 | |
| SCHEMBL22470576 | 0.84 | SCN1A (0.38) | GRM2SCN10ASCN1ASCN4AKCNH2 | |
| SCHEMBL31069731 | 0.82 | SCN1A (0.49) | GRM2SCN10ASCN1ASCN4AKCNH2 | |
| SCHEMBL25380407 | 0.82 | SCN1A (0.49) | GRM2SCN10ASCN1ASCN4AKCNH2 | |
| SCHEMBL31069723 | 0.82 | ALKBH1 (0.37) | GRM2SCN10ASCN1ASCN4AKCNH2 | |
| SCHEMBL31069716 | 0.82 | CACNA2D1 (0.45) | GRM2SCN10ASCN1ASCN4AKCNH2 | |
| SCHEMBL25380642 | 0.79 | TNIK (0.39) | SCN10ASCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL31069732 | 0.79 | TNIK (0.39) | SCN10ASCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL31118862 | 0.74 | SCN1A (0.55) | GRM2SCN10ASCN1ASCN4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118556044-A | Fused heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-08-27 | — | — | CN | disclosed |