Methacrylic Acid

Methacrylic Acid

SCHEMBL31070306

C=C(C)C(=O)O.C=Cc1ccccc1C

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TSHR P16473 1/20 0.45
KDM4E B2RXH2 6/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GMNN O75496 1/20 0.41
PMP22 Q01453 1/20 0.41
ACHE P22303 1/20 0.40
HPGD P15428 3/20 0.38
HTT P42858 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AKR1C3 P42330 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C19 P33261 2/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL2810392 1.00 ALDH1A1 (0.45) ALDH1A1TSHRKDM4ELMNASMN1; SMN2
Methacrylic Acid SCHEMBL27548067 0.98 ALDH1A1 (0.44) ALDH1A1TSHRKDM4ELMNASMN1; SMN2
Methacrylic Acid SCHEMBL29044765 0.96 ALDH1A1 (0.42) ALDH1A1TSHRKDM4ELMNASMN1; SMN2
Acetic Acid SCHEMBL27517007 0.90 ALDH1A1 (0.50) ALDH1A1TSHRKDM4ELMNASMN1; SMN2
Bicarbonate SCHEMBL7132638 0.88 ALDH1A1 (0.52) ALDH1A1TSHRKDM4ELMNASMN1; SMN2
Methacrylic Acid SCHEMBL8110276 0.88 KDM4E (0.42) ALDH1A1TSHRKDM4ELMNAHPGD
Methacrylic Acid SCHEMBL301490 0.88 KDM4E (0.42) ALDH1A1TSHRKDM4ELMNAHPGD
Methacrylic Acid SCHEMBL27703285 0.88 ALDH1A1 (0.36) ALDH1A1TSHRKDM4ELMNASMN1; SMN2
SCHEMBL1852841 0.86 ALDH1A1 (0.48) ALDH1A1TSHRKDM4ELMNASMN1; SMN2
SCHEMBL8928653 0.86 AKR1C3 (0.43) ALDH1A1TSHRKDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546316-B Reinforced and toughened polymer polyol and synthesis process thereof 山东隆华新材料股份有限公司 2024-11-05 CN disclosed
CN-118546316-A Reinforced and toughened polymer polyol and synthesis process thereof 山东隆华新材料股份有限公司 2024-08-27 CN disclosed