Methacrylic Acid

Methacrylic Acid

SCHEMBL301490

C=C(C)C(=O)O.C=Cc1ccccc1C=C

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.42
AKR1C3 P42330 1/20 0.42
ALDH1A1 P00352 3/20 0.41
AKT1 P31749 1/20 0.40
HTT P42858 1/20 0.39
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.37
CYP2C9 P11712 1/20 0.37
ELANE P08246 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
TGM2 P21980 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8110276 1.00 KDM4E (0.42) KDM4EHPGDAKR1C3ALDH1A1AKT1
Methacrylic Acid SCHEMBL3020182 0.96 KDM4E (0.41) KDM4EHPGDAKR1C3ALDH1A1AKT1
Methacrylic Acid SCHEMBL4421004 0.94 KDM4E (0.40) KDM4EHPGDAKR1C3ALDH1A1AKT1
Styrene SCHEMBL28745769 0.92 ALDH1A1 (0.52) KDM4EHPGDAKR1C3ALDH1A1AKT1
Methacrylic Acid SCHEMBL641785 0.92 KDM4E (0.39) KDM4EHPGDAKR1C3ALDH1A1AKT1
Methacrylic Acid SCHEMBL126705 0.92 KDM4E (0.39) KDM4EHPGDAKR1C3ALDH1A1AKT1
Methacrylic Acid SCHEMBL27548067 0.91 ALDH1A1 (0.44) KDM4EHPGDAKR1C3ALDH1A1AKT1
Methacrylic Acid SCHEMBL2810392 0.88 ALDH1A1 (0.45) KDM4EHPGDAKR1C3ALDH1A1AKT1
Methacrylic Acid SCHEMBL3260705 0.88 MAPT (0.50) KDM4EHPGDAKR1C3ALDH1A1LMNA
Methacrylic Acid SCHEMBL31070306 0.88 ALDH1A1 (0.45) KDM4EHPGDAKR1C3ALDH1A1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115492-A1 AN ORODISPERSIBLE PHARMACEUTICAL SOLID DOSAGE FORM OF RASAGILINE INTAS PHARMACEUTICALS LTD. (IN) 2024-04-11 US claimed
CN-110216748-B Aldehyde-free UV wood board with antibacterial function and preparation process thereof 千年舟新材科技集团股份有限公司 2024-01-09 CN claimed
EP-4284336-A1 AN ORODISPERSIBLE PHARMACEUTICAL SOLID DOSAGE FORM OF RASAGILINE Intas Pharmaceuticals Ltd. (IN) 2023-12-06 EP claimed
CN-116904071-A Plant-based negative oxygen ion coating and preparation method thereof 龙牌涂料(北京)有限公司 2023-10-20 CN claimed
US-20230285388-A1 PHARMACEUTICAL RESINATE COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF RHODES PHARMACEUTICALS L.P. 2023-09-14 US claimed
US-11690840-B2 Pharmaceutical resinate compositions and methods of making and using thereof RHODES PHARMACEUTICALS L.P. (US) 2023-07-04 US claimed
CN-116196297-A Dapoxetine hydrochloride oral instant film agent and preparation method thereof 长沙晶易医药科技股份有限公司 2023-06-02 CN claimed
US-20230134462-A1 COMPOSITE ELECTROLYTE, PROTECTIVE FILM INCLUDING COMPOSITE ELECTROLYTE, PROTECTED NEGATIVE ELECTRODE INCLUDING THE PROTECTIVE FILM, AND LITHIUM METAL BATTERY INCLUDING THE PROTECTED NEGATIVE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2023-05-04 US claimed
US-11600815-B2 Composite electrolyte, protective film including composite electrolyte, protected negative electrode including the protective film, and lithium metal battery including the protected SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-03-07 US claimed
CN-115304947-A Coating and preparation method thereof 龙牌涂料(北京)有限公司 2022-11-08 CN claimed
CN-1081877-A Spheronization process with charged resins MERCK & CO INC (US) 1994-02-16 CN claimed
EP-0431759-B1 Process for the preparation of a ranitidine resin absorbate GLAXO GROUP LTD (GB) 1994-01-12 EP claimed
WO-1994000111-A1 SPHERONIZATION PROCESS USING CHARGED RESINS MERCK & CO., INC. (US) 1994-01-06 WO claimed
US-5219563-A Contacting synthetic cation exchange resin with ranitidine or salt to form complex GLAXO GROUP LIMITED (GB) 1993-06-15 US claimed
US-5032393-A Ranitidine flavor masking GLAXO GROUP LIMITED (GB) 1991-07-16 US claimed
EP-0431759-A1 Process for the preparation of a ranitidine resin absorbate GLAXO GROUP LIMITED (GB) 1991-06-12 EP claimed
EP-0226884-B1 SYSTEM FOR THE CONTROLLED-RATE RELEASE OF ACTIVE SUBSTANCES JAGOTEC AG (CH) 1990-11-22 EP claimed
CN-1037651-A DRUG ADSORBATES GLAXO GROUP LTD (GB) 1989-12-06 CN claimed
US-4230804-A ADSORBED ON DIVINYLBENZENE-METHACRYLIC ACID COPOLYMER, CROSSLINKED WITH AN ALDEHYDE BEECHAM GROUP LIMITED (GB) 1980-10-28 US claimed
US-4083782-A ION EXCHANGING USING A CROSSLINKED METHACRYLIC ACID COPOLYMER IN THE ALKALI METAL OR AMMONIUM FORM ROHM AND HAAS COMPANY (US) 1978-04-11 US claimed