Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.35 |
| ▸ | RASGRP3 | Q8IV61 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070553 | 0.82 | MAPT (0.39) | KMT2ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL31444544 | 0.80 | MEN1 (0.42) | MEN1KMT2AMAPK1NAMPTDDB1 | |
| SCHEMBL31444546 | 0.80 | MEN1 (0.42) | MEN1KMT2AMAPK1NAMPTDDB1 | |
| SCHEMBL28241356 | 0.79 | CHRM3 (0.44) | MEN1KMT2AMAPK1NAMPT | |
| SCHEMBL31070552 | 0.79 | SLC6A4 (0.47) | MEN1KMT2ASLC6A4MAPK1SLC6A2 | |
| SCHEMBL5184687 | 0.76 | NAMPT (0.46) | MEN1KMT2AMAPK1NAMPTBCHE | |
| SCHEMBL31374623 | 0.76 | NAMPT (0.42) | MEN1KMT2AMAPK1NAMPTDDB1 | |
| SCHEMBL29029874 | 0.76 | NAMPT (0.42) | MEN1KMT2AMAPK1NAMPTDDB1 | |
| SCHEMBL8222142 | 0.75 | ADAM17 (0.50) | MEN1KMT2AMAPK1NAMPTMAPT | |
| SCHEMBL31070478 | 0.75 | SLC6A2 (0.51) | MEN1KMT2ASLC6A4MAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |